Pharmaceutical and containment solutions
Safe and efficient machinery for active substances, excipients and active ingredients
HECHT Technologie supplies customised solutions for safe pharmaceutical processes.
HECHT Systems for the pharmaceutical industry: this combination has stood for quality, safety and efficiency in the handling of sensitive substances for over 45 years.
The pharmaceutical industry is subject to the most stringent requirements, which is why quality, safety and precision are the top priorities in every pharmaceutical process. Our solutions enable safe, dust-free and efficient handling of valuable or highly potent active ingredients, even with the highest requirements up to OEB 5. We support you in the qualification of machines and systems as well as the reliable validation of your cleaning processes, and of course we also comply with FDA requirements and other regulations.
We have been working in partnership with leading companies in the pharmaceutical industry for over 45 years. With our expertise, we develop customised solutions that are precisely tailored to your pharmaceutical processes, from planning and design through to commissioning!
References from pharmaceutical practice
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HECHT - Pfizer - High-containment production facility - in co-operation with HECHT Technologie
Pfizer is expanding its production to a resource-efficient and sustainable solution with the new HighCon system. HECHT Technologie supplied the complete feeding station with big bag, sack and drum emptying devices for highly reliable powder handling. Another example of HECHT's expertise in pharmaceutical powder technology.
Away with rigid processes: the supply of raw materials in the continuous production of medicinesPfizer is expanding its production to a resource-efficient and sustainable solution with the new HighCon system. HECHT Technologie supplied the complete feeding station with big bag, sack and drum emptying devices for highly reliable powder handling. Another example of HECHT's expertise in pharmaceutical powder technology.
Supply of raw materials in continuous productionPfizer is expanding its production to a resource-efficient and sustainable solution with the new HighCon system. HECHT Technologie supplied the complete feeding station with big bag, sack and drum emptying devices for highly reliable powder handling. Another example of HECHT's expertise in pharmaceutical powder technology.
Large-scale plant for the production of surgical and orthopaedic fillers
HECHT product range for the life sciences and pharmaceutical industry
LBK-EC big bag vullen
The liner filling head for drums and big bags does not require O-rings, offers simple 3-button operation and increases safety and convenience.
Containment sampling stick
Patented, mobile solution for safe sampling up to OEB 5. Simple, cost-saving and contamination-free - ideal for sensitive substances.
SoliValve® double cone system
Fully automatic, low-contamination and precise up to OEB 5. Versatile for big bags & containers - innovative technology without complicated valves.
ProClean Conveyor (PCC)
Pneumatic conveying system for dust-free, safe transport of explosive and toxic bulk materials - flexible, efficient and reliable.
Big bag emptying
Efficient big bag emptying up to OEB 5: safe, low-contamination, ergonomic and modular - perfectly integrated into your production processes.
Big bag filling
Safe and efficient big bag filling with minimal consumables, ergonomic and user-friendly - ideal for sensitive and toxic products.
HECHT process steps for the pharmaceutical industry
Filling
Filling heads and big bag and small container filling stations.
Emptying
Emptying stations for big bags, drums and sacks.
Dosing
Precise dosing and weighing components: Dosing sluices, dosing screw and more.
Disposable technology
Disposable insulators for simple quality assurance: EWI and EPS insulators.
Convey
For conveying powders and granulates: Pneumatic vacuum conveyors and suction shoes.
Sampling
Samplers for every requirement: screw, slide, vacuum samplers and more.
Components
Filling heads, connection systems, loading harnesses and crushers with sieve grater.
Elements
Quickly available and standardised components: Filling heads, connection systems or charging harnesses.
Essentials
Essentials for secure product handling: containment clips, sealing cases, endless films and more.
Validatable cleaning and product safety for the pharmaceutical industry
To ensure the highest standards of hygiene in pharmaceutical production, we integrate efficient cleaning solutions such as WIP, CIP and SIP processes right from the planning process. We also work with you to create a cleaning concept so that the cleaning process for your systems can be validated. At the same time, we reliably protect your products from cross-contamination and contamination by foreign substances - for maximum product safety and regulatory compliance.
Containment solutions for safe personnel and environmental protection in the pharmaceutical industry
In pharmaceutical production, the safe handling of potentially hazardous or highly active solids is essential. Containment systems are therefore categorised into specific classes depending on the application, product and area of use. The product-specific limit values - such as AGW (occupational exposure limit), OEL (Occupational Exposure Limit), ADE (Acceptable Daily Exposure) or OEB (Occupational Exposure Band) - define which system and working method is used.
As an experienced partner, HECHT supports you in selecting the optimum containment - for maximum safety of employees and the environment. Our systems ensure that hazardous substances remain reliably in the process and do not escape to the outside or into the environment.
Seamless documentation and certified technology for pharmaceutical safety
Our system solutions for the pharmaceutical industry enable end-to-end documentation across all interfaces and process steps. This creates transparency, simplifies analyses and supports seamless quality monitoring along the entire process chain.
Thanks to FDA-compliant and certified technologies, we also ensure that the highest containment requirements are met - for standard-compliant processes and maximum safety in production.
HECHT automation for the pharmaceutical industry
HECHT automation for the pharmaceutical industry
Automation solutions for the highest demands in the pharmaceutical industry
HECHT Technologie offers GAMP 5-compliant system solutions for the safe, efficient and reproducible handling of sensitive powders. Whether filling, emptying, conveying, dosing or sampling - our automation systems fulfil GMP and FDA requirements and can be seamlessly integrated into existing MES and SCADA structures. Track & Trace and electronic audit trails guarantee complete traceability - for maximum process reliability and compliance.
HECHT services
Would you like to test, rent or lease a HECHT machine? Or do you need support with a pharmaceutical process?
FAQ
What containment requirements apply to API production in the pharmaceutical industry?
In the production of active pharmaceutical ingredients (APIs), the containment requirement is determined by the OEB class of the substance, defined in a toxicologically substantiated OEL. Highly potent APIs and cytotoxics generally fall under OEB 4 or 5, requiring closed transfer, SMEPAC validation and GMP documentation (URS, DQ, IQ, OQ) in line with GMP Annex 1. Each coupling, filling and emptying point must be assessed individually for leakage risk. A supplier with a complete validation package and local service is essential to limit inspection risk.
Up to which OEB level do HECHT systems offer containment for pharmaceutical processes?
Our solutions enable safe, dust-free and efficient handling of valuable or highly potent active ingredients, even with the highest requirements up to OEB 5. We support you in the qualification of machines and systems as well as the reliable validation of your cleaning processes, and of course we also comply with FDA requirements and other regulations.
What is a SMEPAC measurement?
SMEPAC (Standardized Measurement of Equipment Particulate Airborne Concentration) is the internationally recognised ISPE method for objectively measuring the containment performance of equipment. The measurement determines how many particles are released during an operation such as coupling, filling or emptying, expressed in ug/m3. This demonstrates whether a system meets the required OEB class rather than only claiming it on paper. A SMEPAC-validated system is essential during EMA and FDA inspections. HECHT performs SMEPAC tests using API surrogates in its Test & Trial Centre.